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NexGard PLUS Chews One-And-Done Monthly Protection for Dogs

Next-Level Protection for Dogs. Fleas. Ticks. Roundworms. Hookworms. Heartworm Disease. NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets)
NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets)

NexGard PLUS

NexGard® PLUS protects your dog from parasites month after month. Talk to your vet to see if a NexGard® PLUS prescription is right for your dog.

Reported side effects of NexGard® PLUS include vomiting, itching, diarrhea, and lethargy. Use with caution in dogs with a history of seizures or neurologic disorders.

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Protect Your Dog

One monthly dose delivers a full 30 days of protection from fleas, ticks, heartworm disease, roundworms, and hookworms.

Beef-Flavored Chew

Tasty beef-flavored chew that’s designed to be easy to give.

Protect your puppy from the start

NexGard PLUS is safe for puppies at least 8 weeks of age weighing 4 lbs or more.

Vet Recommended

Talk to your vet about protecting with NexGard PLUS, available by prescription.

Product Details

NexGard® PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) chews deliver next-level protection all in one tasty soft chew. The one-and-done monthly beef flavored NexGard PLUS chews provide protection against fleas, ticks, heartworm disease, roundworms, and hookworms. NexGard PLUS chews are safe and approved for puppies as young as 8 weeks old, weighing 4 pounds or more.

From the maker of veterinarian-recommended HEARTGARD® Plus (ivermectin/pyrantel)1 chews, tasty NexGard® PLUS chewables provide convenient, monthly parasite protection for the dog you love. Use with caution in dogs with a history of seizures or neurological disorders. Dogs need parasite protection year-round. NexGard PLUS chews are designed for monthly dosing that’s a delight for your dog month after month.

Fleas pose an ever-present risk for dogs in many parts of the country. While the risk of flea infestations may be higher during warmer months, they can occur at any point throughout the year. NexGard PLUS chewables kill adult fleas fast, before they can lay eggs, for a full month. NexGard PLUS chewables are also approved to kill five species of ticks – including the four species that are most commonly found on dogs in the US.2

Heartworm disease is a serious condition that can cause permanent damage – and just one bite from an infected mosquito could put your pet at risk for this potentially deadly disease. Cases of heartworm disease have been reported in all 50 states – in both indoor and outdoor pets.3 The American Heartworm Society recommends that all pets receive heartworm disease prevention year-round. Ask your veterinarian about heartworm disease prevention for dogs with monthly NexGard PLUS chewables. All dogs should be tested for heartworms prior to starting a heartworm disease preventive.

With NexGard PLUS chewables, you’re protecting your dog from fleas and ticks, PLUS heartworm disease, 3 species of hookworms, and 2 species of roundworms – all with the tasty beef-flavored chew that’s designed for monthly dosing that’s a delight for your dogs.

  • Convenient one-and-done monthly dosing for parasite protection for dogs
  • Provides flea and tick protection for dogs
  • Kills adult fleas and 5 species of ticks
  • Effective prevention of heartworm disease
  • Treats and controls 3 species of hookworms and 2 species of roundworms
  • Tasty, beef-flavored soft chew that’s designed to be a delight for your dog
  • Safe for puppies as young as 8 weeks of age, weighing 4 pounds or more

NexGard® PLUS chews can be administered with or without food. Care should be taken to ensure that the dog consumes the complete dose, and that part of the dose is not lost or refused. If a dose is missed, administer a NexGard PLUS chew and resume a monthly dosing schedule. Please review full prescribing information.

Afoxolaner, Moxidectin, Pyrantel

IMPORTANT SAFETY INFORMATION:
NexGard PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) is safe for puppies at 8 weeks, weighing 4 pounds or more. Use with caution in dogs with a history of seizures or neurological disorders. The most frequently reported adverse reactions are diarrhea, vomiting, lethargy, and itching. Dogs should be tested for existing heartworm infection prior to starting a preventive. For full prescribing information, talk to your vet, call 888 - 637 - 4251, or visit NexGardPLUS.com.

NexGard® is a registered trademark of Boehringer Ingelheim Animal Health France, used under license. ©2025 Boehringer Ingelheim Animal Health USA Inc., Duluth, GA. All rights reserved.

Frequently Asked Questions

NexGard® PLUS is used to protect your dog from fleas and ticks, PLUS heartworm disease, roundworms, and hookworms. NexGard PLUS chews are available in a delicious, beef-flavored soft chew that makes monthly dosing a delight for your dogs. For each monthly dose, a chew can be given with or without food. See the product label for full dosing instructions, and always check with your vet regarding their recommendations for your pet.

NexGard® PLUS chews kill fleas fast before they can lay eggs. In a well-controlled laboratory study, afoxolaner alone began to kill fleas 4 hours after initial administration and was >99% effective at 8 hours. NexGard PLUS chews provide powerful protection against fleas and ticks for a full month.

NexGard PLUS chews work to prevent heartworm disease by killing any heartworm larvae that were acquired in the previous month. That’s why it is so important for your dog to receive the appropriate dose of NexGard PLUS chews every month, year-round.

The pyrantel in NexGard PLUS chews is a dewormer that treats and controls 3 species of hookworms and 2 species of roundworms.

You are likely seeing NEW fleas on your pet, which are jumping on your dog as it moves through infested areas. These fleas will be killed quickly by NexGard® PLUS chews before they can reproduce. Depending on the severity of an already existing infestation, you may continue to see new fleas jumping on your pet for three months or more (depending on environmental conditions). To prevent new infestations, continue to give NexGard PLUS chews MONTHLY throughout the year.

Adult fleas – the ones that you see on an infested pet – make up only ~5% of the total flea population. The developing stages (flea eggs, larvae, and pupae) make up the other ~95%. These developing stages can be found anywhere an infested animal spends time. Commonly infested animals, which spread flea eggs throughout their surroundings, include untreated pets, feral cats, opossums, raccoons, coyotes, etc.4

Treatment with NexGard® PLUS chews may begin at any time of the year. It is recommended to treat your dog month after month, year-round no matter the season.

Yes – it’s a common misconception that indoor pets aren’t exposed to parasites.

Fleas are opportunists. Even if your dog only goes outside to do their business, they’re at risk of infestations from fleas and ticks. Fleas can even “hitchhike" into a home on people, and then jump to infest dogs. An infested pet will spread flea eggs throughout the house, which can survive in your carpet or the crannies of your wood floors and then mature to infest other animals in your home.

Heartworms are transmitted by mosquitoes. It only takes one mosquito bite to transmit heartworms to your dog – so dogs can be exposed in a very short amount of time. And unfortunately, mosquitoes commonly make their way indoors in search of hosts. Even indoors, pets aren’t safe from the threat.

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Powered by Costco Health Solutions. Costco Member Prescription Program (CMPP) is a direct-to-members savings program administered by Costco Health Solutions, Inc. and Ventegra Inc. Participating pharmacies are subject to change without notice and are not available in all areas. CMPP is not insurance or intended as a replacement for insurance. Claims submitted for coverage under publicly funded programs (e.g. Medicare, Medicaid, etc.) or private insurance are not eligible for CMPP participation. Shipping and handling cost are not included in the price. Costco Health Solutions, Inc. 845 Lake Drive Issaquah, WA 98027 https://www.costcohealthsolutions.com/. Data on file at Boehringer Ingelheim Saleh MN, Sundstrom KD, Duncan KT, et al. Show us your ticks: a survey of ticks infesting dogs and cats across the USA. Parasites & Vectors. 2019;12(595). https://doi.org/10.1186/s13071https://doi.org/10.1186/s13071-019-3847-3019-3847-3. Heartworm Parasite Prevalence Maps. Companion Animal Parasite Council. https://capcvet.org/maps/#/2023/all-year/heartworm-canine/dog/united-states. Accessed May 22, 2023. Dryden M. Biology of fleas of dogs and cats. Compend Contin Educ Vet. 1993(4):569-579.